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The Effect of Artificial Sweetener Aspartame on Gut Microbiota

The Effect of Artificial Sweetener Aspartame on Gut Microbiota

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121173
Enrollment
Unknown
Registered
2026-03-26
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Experimental group:Aspartame

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Healthy male or female; 2. Age between 18 and 70 years old; 3. BMI index between 19 and 25 kg/m^2; 4. Weight has remained stable in the past three months.

Exclusion criteria

Exclusion criteria: 1. Has a habit of smoking or excessive drinking; 2. Pregnant or lactating women; 3. Has metabolic or gastrointestinal diseases (Type 1 and Type 2 diabetes, inflammatory bowel disease, irritable bowel syndrome, phenylketonuria); 4. Used probiotics or antibiotics within the six months prior to the study.

Design outcomes

Primary

MeasureTime frame
Gut microbiota;—

Secondary

MeasureTime frame
Bacterial metabolites;—

Countries

China

Contacts

Public ContactZeng yong

West China Hospital of Sichuan University

Zengyong@medmail.com.cn+86 28 85422114

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026