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Development and Validation of a Model to Predict the Risk of Intraoperative and Postoperative Hypoglycemia in Patients Undergoing Surgery for Gastrointestinal Tumors

Construction and Validation of a Risk Prediction Model for Perioperative Hypoglycemia in Patients with Gastrointestinal Tumors: A Retrospective Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121162
Enrollment
Unknown
Registered
2026-03-26
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer:Gastric cancer / Stomach cancer:Small intestine cancer:Duodenal cancer:Colorectal cancer:Liver cancer / Hepatic cancer:Pancreatic cancer:Bile duct cancer / Cholangiocarcinoma:Gallbladder cancer:Hypoglycemic event(s)

Interventions

Observation Group:None

Sponsors

The First Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-80 years old; 2. Pathologically diagnosed with esophageal cancer, gastric cancer, colorectal cancer, liver cancer, pancreatic cancer, bile duct cancer, or gallbladder cancer; 3. Scheduled to undergo surgical treatment; 4. Complete clinical data available.

Exclusion criteria

Exclusion criteria: 1. Presence of severe cognitive impairment or consciousness disorders; 2. Complicated by severe dysfunction of major organs (e.g., heart, liver, brain, lung, kidney) or metabolic diseases; 3. Patients who did not undergo surgery or only received palliative procedures such as exploratory laparotomy; 4. Hypoglycemic events occurring outside the inpatient ward unit.

Design outcomes

Primary

MeasureTime frame
Incidence of hypoglycemia;

Secondary

MeasureTime frame
Postoperative complications;Length of hospital stay;Mortality rate;Hospitalization cost;Demographic and medical history data (sex, age, BMI, smoking history, alcohol history, diabetes, hypertension, renal disease history, liver disease history, hemodialysis history, medication history);Laboratory parameters (albumin, hemoglobin, neutrophil count, CRP, glycated hemoglobin, total bilirubin, alanine aminotransferase, urea nitrogen, fasting blood glucose, creatinine concentration, triglycerides, high-density lipoprotein, glomerular filtration rate);Tumor-related indicators (tumor type, tumor stage, neoadjuvant therapy prior to surgery, treatment phase, surgical approach, operation duration, fasting duration, nutritional modality, enteral nutrition rate, formula);Medication use (somatostatin, insulin, sulfonylureas, glinides, glucocorticoids, postoperative analgesics);Preoperative glucose variability (standard deviation or coefficient of variation, CV);

Countries

China

Contacts

Public ContactZhu Huidi

The First Affiliated Hospital of Zhejiang University School of Medicine

hzzhuhuidi0505@yeah.net+86 571 87237931

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026