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Retrospective Cohort Study on the Impact of Total Knee Arthroplasty on Knee Function, Gait, and Muscle Activation in Patients with Osteoarthritis

Retrospective Cohort Study on the Impact of Total Knee Arthroplasty on Knee Function, Gait, and Muscle Activation in Patients with Osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121150
Enrollment
Unknown
Registered
2026-03-26
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Interventions

Total Knee Arthroplasty Group:None
Healthy Control Group:None

Sponsors

First Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Knee replacement group: (1) Age 40-80 years old; (2) Patients who underwent unilateral total knee arthroplasty due to OA; (3) The operation process was strictly in accordance with the guidelines; (4) Complete preoperative baseline and follow-up data at 3, 6, and 12 months after surgery. Healthy controls: (1) Age 40-80 years old; (2) No history of knee pain (KOOS pain score >90, VAS pain score <2/10); (3) The range of motion of the knee joint was normal, without biomechanical abnormalities of the lower limbs, and the neuromuscular function was normal. (4) The collected data were complete.

Exclusion criteria

Exclusion criteria: Knee replacement group: (1) complicated with other serious injuries of the lower limbs, such as collateral ligament injury, fracture or other injuries requiring surgical intervention; (2) patients with a history of hip or knee surgery; (3) patients with cardiovascular and cerebrovascular, liver and kidney, hematopoietic, nervous system, lumbar spine and other serious diseases. Healthy controls: Patients with cardiovascular and cerebrovascular, liver and kidney, hematopoietic, nervous system, lumbar spine and other serious diseases.

Design outcomes

Primary

MeasureTime frame
Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC);—

Secondary

MeasureTime frame
Range of Motion, ROM;Knee Society Score,KSS;36-Item Short-Form Health Survey;Tegner Activity Scale;Gait parameters;Muscle Strength Testing;Surface electromyography parameters;motor threshold;Balance and Proprioception;Single Leg Hop Test;Dynamic digital radiography parameters;7-Tesla Magnetic Resonance Imaging of the Knee Joint parameters;Functional neuroimaging parameters;—

Countries

China

Contacts

Public ContactLin Guo

First Affiliated Hospital of Army Medical University

guolin6212@163.com+86 199 3817 7463

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026