Refractory cardiac arrest
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 - 70 years old (the age limit can be relaxed if the patient has good organ function and a good prognosis of neurological function after evaluation); 2. When cardiac arrest occurs, there is a witness, and a bystander performs traditional cardiopulmonary resuscitation, with the time interval from the occurrence of cardiac arrest to the start of traditional cardiopulmonary resuscitation not exceeding 5 minutes; 3. The causes of cardiac arrest include reversible etiologies such as cardiogenic causes, pulmonary embolism, severe hypothermia, drug poisoning, trauma, and acute respiratory distress syndrome. 4. Traditional cardiopulmonary resuscitation is performed for 20 minutes without the recovery of spontaneous circulation, with hemodynamic instability, or with the recovery of spontaneous circulation but the inability to maintain a spontaneous heart rhythm.
Exclusion criteria
Exclusion criteria: 1. Infectious diseases such as hepatitis B, hepatitis C, AIDS, syphilis, etc.; 2. Suffering from hematological system diseases, such as: hematological malignancies, aplastic anemia, idiopathic thrombocytopenia, etc. 3. In addition to the blood system, suffering from malignant tumors of other systems; 4. Patients who have received a large amount of plasma or platelets during hospitalization or recently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality;Molecular marker; | — |
Countries
China
Contacts
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology