Knee Osteoarthritis
Conditions
Interventions
Experimental group:Patients in the experimental group received topical flurbiprofen gel patch combined with moxibustion on the affected knee. Flurbiprofen gel patch, containing 40 mg of flurbiprofen p
Moxibustion alone control group:Heat-sensitive moxibustion was adopted. Moxibustion-sensitive points were detected around the knee joint in the region composed of Yinlingquan (SP9), Yanglingquan (GB34
Flurbiprofen patch alone control group:Patients in the experimental group received topical flurbiprofen gel patch combined with moxibustion on the affected knee. Flurbiprofen gel patch, containing 40
Sponsors
The First People's Hospital of Longquanyi District, Chengdu
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the Western medical diagnostic criteria for osteoarthritis (Orthopedics, People's Medical Publishing House); 2. No gender restriction, aged 18–60 years; 3. No use of other therapeutic drugs (such as analgesics, hormones) or surgical treatment within the past 1 month; 4. Voluntarily participate in and comply with the treatment protocol, with signed informed consent; 5. No severe neurological, psychiatric or somatic diseases.
Exclusion criteria
Exclusion criteria: 1. Received previous therapeutic interventions that may affect the efficacy; 2. Complicated with severe underlying diseases such as tumors, cardiovascular and cerebrovascular diseases, hematological diseases, and digestive system diseases; 3. Patients with hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) including loxoprofen and flurbiprofen; 4. Patients with asthma or allergic constitution to moxibustion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom improvement rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Western Ontarioand McMaster Universities Osteoarthritis Index (WOMAC) score;VAS score;IL-1ß;TNF-a; | — |
Countries
China
Contacts
Public ContactWu Linfeng
The First People's Hospital of Longquanyi District, Chengdu
Outcome results
None listed