Patients with post-stroke aphasia.
Conditions
Interventions
tTIS Thalamus Group:Transcranial Time-domain Interference Stimulation (tTIS) treatment
base frequency 2000Hz, modulated frequency 10-20Hz, current intensity 1-2mA
combined with conventional speech rehabilitation therapy
tTIS Thalamus Sham Stimulation Group:Transcranial Time-domain Interference Stimulation (tTIS) treatment
base frequency 2000Hz, modulated frequency 0Hz, current intensity 1-2mA (no envelope electric field effect)
tTIS Left Inferior Frontal Cortex Stimulation Group:Transcranial Time-domain Interference Stimulation (tTIS) treatment
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who have completed imaging examinations such as CT or MRI and are clinically confirmed to have had a stroke. 2. Patients with first clinically diagnosed stroke in the subacute phase. 3. Aphasia confirmed by the Western Aphasia Inventory (WAB) has no contraindications for fMRI and EEG. 4. Able to cooperate with Transcranial Temporal Interference Stimulation (tTIS) treatment. 5. Aged 18–75 years. 6. Has provided consent and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Vital signs are not yet stabilized. 2. Severe infection or skin breakdown at the stimulation site. 3. Contraindications to electrical stimulation therapy. 4. Poor adherence to the study treatment protocol. 5. Severe dysarthria. 6. Neglect, severe visual impairment, or hearing loss.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Aphasia Battery (WAB) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Magnetic Resonance Imaging (fMRI);Electroencephalography (EEG); | — |
Countries
China
Contacts
Public ContactZhang Jie
Zhejiang Provincial People's Hospital
Outcome results
None listed