local tumor progression of hepatocellular carcinoma
Conditions
Interventions
Primary hepatocellular carcinoma group:None
Local tumor progression group:None
Recurrent hepatocellular carcinoma group:None
Sponsors
The First Affiliated Hospital,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old, WHO/ECOG physical status score =80g/L; PLT>=50×10^9/L; Coagulation function test: PT<20s.
Exclusion criteria
Exclusion criteria: 1. Unclear pathological results or incomplete clinical data; 2. Infection, cardiovascular and cerebrovascular diseases, liver, kidney and lung failure or other systemic malignant tumors with significant clinical symptoms. 3. History of unexplained bleeding, severe anemia, bleeding tendency, or uncorrected coagulation dysfunction; 4. Massive ascites; 5. Pregnant or lactating women; 6. Other factors that the investigators believe are not suitable for inclusion or affect the subject's participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nuclear rate;Cell activity;Composition and proportion of immune cell subsets;Cell-to-cell communication (ligand-receptor interaction) strength;Markers of tumor cell heterogeneity;Molecular expression at key immune checkpoints; | — |
Countries
China
Contacts
Public ContactMing Xu
The First Affiliated Hospital,Sun Yat-sen University
Outcome results
None listed