PitNETs.
Conditions
Interventions
Gold Standard:Postoperative follow-up examination, routine blood tests, and enhanced magnetic resonance imaging examination
Index test:FAPI PET/MR local imaging
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Pathological or clinical diagnosis of pituitary neuroendocrine tumor; 2. Pituitary neuroendocrine tumor Knosp grade II-IV or suspected bone invasion or breach of the sellar diaphragm with surgical indications; 3. Age between 18 and 75 years; 4. No restriction on gender; 5. Voluntary participation and signing of informed consent form.
Exclusion criteria
Exclusion criteria: 1. Contraindications for magnetic resonance examination: functional electronic devices and various stimulators (such as pacemakers, cochlear implants, etc.) implanted in the body; implants made of ferromagnetic materials (such as those containing iron, cobalt, nickel, etc.). Infusion devices implanted in the body, such as insulin or other infusion pumps; 2. Individuals with claustrophobia; 3. Patients unable to lie flat for 30 minutes during clinical assessment; 4. History of severe systemic diseases or mental illnesses affecting the heart, liver, kidneys, brain, blood, immune system, etc. 5. Individuals with fertility plans in the past two years or pregnant women; 6. Currently participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Area Under the Receiver Operating Characteristic Curve; | — |
Countries
China
Contacts
Public ContactLin Shaojian
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed