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Cool Oxygen Nebulization for Postoperative Thirst in the PACU

Impact of Low-Temperature Oxygen Nebulization on Postoperative Thirst in General Anesthesia Patients during PACU Recovery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121083
Enrollment
Unknown
Registered
2026-03-25
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative thirst

Interventions

Conventional Oxygen Therapy Group:conventional oxygen nebulization
Low-Temperature Nebulization Group:chilled normal saline
Room Temperature Nebulization Group:normal saline at room temperature

Sponsors

The Peoples Hospital of Pingyang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age > 18 years, regardless of gender. 2.Elective surgery with endotracheal general anesthesia. 3.Alert and oriented preoperatively, with the ability to communicate effectively. 4.ASA physical status classification II to III, with essentially normal cardiac and pulmonary function, and able to tolerate routine anesthesia. 5.Transferred to the Post-Anesthesia Care Unit (PACU) and successfully extubated with stable consciousness recovery. 6.The patient is awake, cooperative, and oriented, apable of comprehending assessment instructions and able to subjectively report sensations such as thirst and dryness. 7.The patient provided informed consent to participate in the trial and voluntarily agreed to cooperate with the interventions and follow-up assessments of this study.

Exclusion criteria

Exclusion criteria: 1.Patients requiring special interventions post-extubation (e.g., laryngospasm, severe cough). 2.Patients requiring prolonged mechanical ventilation with continued intubation after surgery. 3.History of oral or pharyngeal surgery/lesions (e.g., head and neck surgery, radiotherapy history, Sjögren's syndrome) leading to abnormal baseline salivary secretion or sensory dysfunction; presence of active oral mucosal ulcers or infections. 4.Severe chronic obstructive pulmonary disease (COPD) or uncontrolled asthma, resulting in poor tolerance to nebulization; uncontrolled hyperglycemia in diabetic patients causing polydipsia; use of medications affecting salivary secretion (e.g., anticholinergics). 5.Hypersensitivity or intolerance to the low-temperature stimulation of 0.9% normal saline (stored at 2–8°C). 6.History of salivary gland dysfunction. 7.Cognitive impairment or communication barriers preventing cooperation with the study protocol.

Design outcomes

Primary

MeasureTime frame
Thirst Intensity (NRS) ;Xerostomia Facial Expression;Oral Mucosa Moisture Grade;Resting Salivary Flow Rate;Postoperative Time (Flatus & Defecation);

Countries

China

Contacts

Public ContactYuting Cheng

The Peoples Hospital of Pingyang

1003700532@qq.com+86 577 6373 0082

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026