Pertussis
Conditions
Interventions
Control group:According to the vaccine package insert, administer three doses following either the 3-4-5 month schedule or the 2-3-4 month schedule.
Intervention Group:Administer three doses following the 2-4-6 month schedule.
Sponsors
Chinese Center for Disease Control and Prevention
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy, resident infants who meet the age requirement of 2 months for the intervention group and 3 months for the control group on the day of enrollment; 2. Infants who have completed the required National Immunization Program vaccinations prior to reaching 2 months of age (intervention group) or 3 months of age (control group); 3. Parents or legal guardians of the infant have signed the informed consent form; 4. Parents or legal guardians of the infant are able to attend all scheduled visits and comply with all study procedures; 5. Axillary temperature <= 37.0°C.
Exclusion criteria
Exclusion criteria: 1. Infants who have previously received vaccines containing acellular DTP components, Hib vaccines, or their combination vaccines; 2. Neonates born at less than 37 weeks of gestation or with a birth weight of 37.0°C; 7. Other conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seroconversion proportion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Antibody level; | — |
Countries
China
Contacts
Public ContactYin Zundong
Chinese Center for Disease Control and Prevention
Outcome results
None listed