Insomnia disorder
Conditions
Interventions
Observation group:None
Sponsors
The First People's Hospital of Yunnan Province
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age of 18-65 years old, male or female; BMI 18-30 kg/m². 2. DSM-5 insomnia disorder >=3 months, >=3 nights/week. 3. ISI >=15 (moderate and above). 4. PSG of adaptation night: AHI <10 /h, PLMI (with arousal) <15 /h. 5. Liver and kidney function, blood routine were normal, and there was no history of cardiovascular and cerebrovascular diseases. 6. Provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Other major sleep disorders: moderate to severe sleep apnea (AHI =10 /h), narcolepsy, REM behavior disorder, circadian rhythm sleep-wake disorder (delayed >2 h shift). 2. Major depression (HAMD-17 >17), bipolar disorder, psychotic disorder. 3. Significant cognitive impairment (MoCA =15) or drug abuse. 10. Any condition judged by the investigator to affect adherence or safety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep microstructure and quality;Dose-response relationship; | — |
Countries
China
Contacts
Public ContactHuijie Tang
The First People's Hospital of Yunnan Province
Outcome results
None listed