painless endoscopic injection sclerotherapy for cirrhotic patients in China
Conditions
Interventions
oliceridine group:The patients in the oliceridine group were given a dose of 0.03 mg/kg oliceridine
sufentanil group: The patients in the sufentanil group were given a dose of0.15 µg/kg sufentanil
Sponsors
Beijing You'an Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients with cirrhosis of various etiologies; 2.American Society of Anesthesiologists (ASA) physical status ?–?; 3. Aged 18–65 years, regardless of gender; 4. Liver function classified as Child-Pugh grade A or B; 5. Meeting the indications for painless EIS; 6.Patients who agreed to undergo sedated or anesthetized gastroscopy and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Non-cirrhotic patients; 2. Patients with contraindications to conventional gastroscopy; 3. Patients who refused sedation or anesthesia for gastroscopy; 4. Patients allergic to components of sedatives or anesthetics; 5. Patients unable to complete the questionnaire due to various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs including SBP, DBP, MAP, HR, RR, and SpO?;Incidence of adverse reactions: including specific adverse reactions (nausea, vomiting, dizziness, fever, and drowsiness) and other non-specific adverse reactions.;Anesthesia satisfaction of patients and gastroscopists; | — |
Countries
China
Contacts
Public ContactGuan Lei
Beijing You'an Hospital, Capital Medical University
Outcome results
None listed