Adolescent Idiopathic Scoliosis (AIS): It is a common three-dimensional musculoskeletal deformity of the spine among adolescents aged 10-18 years, and is one of the main types of spinal deformities. Its clinical manifestations include: somatic structural abnormalities, motor dysfunction, accompanied by proprioceptive dysfunction, postural control deficits, and structural abnormalities of the centr
Conditions
Interventions
Control group:No intervention
Adolescent idiopathic scoliosis:No intervention
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for the AIS Group 1. Age between 10 and 18 years. 2. Meets the diagnostic criteria for idiopathic scoliosis established by the Scoliosis Research Society, with a Cobb angle >10° on anteroposterior and lateral standing X-rays. 3. Normal ankle joint range of motion as measured by a standardized goniometer, specifically dorsiflexion = 20° and plantarflexion = 40°. 4. No contraindications for magnetic resonance imaging (MRI), such as the presence of metallic implants or claustrophobia, and ability to cooperate with the fMRI examination protocol. 5. Signing of a written informed consent form; If the participant is under 16 years of age, the informed consent form must be signed in the presence of a legal guardian. Healthy control group: 1. Age 10–18 years; 2. No history of spinal deformities, neuromuscular diseases, or orthopedic surgery; 3. Signed written informed consent; 4. No contraindications for MRI examination.
Exclusion criteria
Exclusion criteria: 1. Individuals with implanted metal devices or who carry ferromagnetic objects (which do not meet MRI safety requirements); 2. Individuals with severe cognitive impairment or mental illness (who are unable to cooperate in completing study tasks); 3. Individuals who have used central nervous system-active medications within 3 months prior to evaluation; 4. Individuals who have undergone spinal surgery or have a condition that affects proprioception.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Key Brain Region Activation Intensity (ß Value); | — |
Secondary
| Measure | Time frame |
|---|---|
| Ankle Joint Reposition Error Test (AJRE) Mean Absolute Error (MAE); | — |
Countries
China
Contacts
Public ContactGuohang Huang
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed