congenital hydronephrosis
Conditions
Interventions
Case group:None
Sponsors
Children's Hospital,Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: 1. Diagnostic Criteria: Confirmed diagnosis of congenital hydronephrosis via abdominal ultrasound, meeting the criteria for urinary tract dilation grading (Grades I–III), defined as a fetal renal pelvis anteroposterior diameter of >= 4 mm or a postnatal renal pelvis anteroposterior diameter of >= 7 mm, or accompanied by symptoms such as calyceal dilation or changes in renal parenchyma. 2. Feasibility of Follow-up: The guardian commits to cooperating with a 3-year follow-up, is able to attend regular examinations at the research center, and has stable contact information. 3. Informed Consent: The legal guardian voluntarily participates in this study and signs a written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Presence of other severe congenital anomalies, such as congenital heart disease, biliary atresia, spina bifida, or other conditions that may interfere with follow-up or prognosis evaluation. 2.Secondary hydronephrosis caused by acquired factors including urinary tract tumors, calculi, trauma, or confirmed genetic metabolic diseases. 3.Prior intervention before enrollment, including hydronephrosis-related surgical treatment (e.g., pyeloplasty) or medical intervention (e.g., long-term diuretic use). 4.Severe underlying diseases, such as severe infection, respiratory failure, renal failure (glomerular filtration rate < 30 mL/min/1.73 m²), or other conditions incompatible with long-term follow-up. 5.Legal guardian is unable to understand study procedures due to mental illness, cognitive impairment, or refuses to comply with follow-up and data collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remission rate of hydronephrosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of urinary tract infection (UTI);Intervention rate;Progression rate of hydronephrosis;renal function; | — |
Countries
China
Contacts
Public ContactGuangjie Chen
Children's Hospital,Zhejiang University School of Medicine
Outcome results
None listed