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Neuromodulatory Effects and Safety of Continuous Theta Burst Stimulation in Individuals with Sleep Bruxism

Neuromodulatory Effects and Safety of Continuous Theta Burst Stimulation in Individuals with Sleep Bruxism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121020
Enrollment
Unknown
Registered
2026-03-24
Start date
2026-03-31
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep bruxism

Interventions

cTBS group:Participants in the experimental group received accelerated continuous theta burst stimulation (a-cTBS) targeting the bilateral orofacial motor cortex. Each burst consisted of three pulses
sham group:Participants in the control group received sham stimulation using a tilted coil, which visually, auditorily, and tactilely mimicked real stimulation without producing significant cortical m

Sponsors

Shanghai University of Sport
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Sixty individuals with sleep bruxism were recruited. All participants were right-handed and had normal or corrected-to-normal vision.

Exclusion criteria

Exclusion criteria: 1. History of organic brain disease, traumatic brain injury, cranial surgery, presence of intracranial metal implants, or increased intracranial pressure; 2. Presence of cardiac metal stents, implanted cardiac pacemakers, or other cardiac conductive devices; 3. Use of hearing aids; 4. Personal or family history of epilepsy; 5. History of electroconvulsive therapy.

Design outcomes

Primary

MeasureTime frame
OBC questionnaire;Objective sleep bruxism event count;

Secondary

MeasureTime frame
Sleep quality (Pittsburgh Sleep Quality Index, PSQI);Daytime functioning and self-reported experience;Emotional status (Self-Rating Anxiety Scale, SAS; Self-Rating Depression Scale, SDS);

Countries

China

Contacts

Public ContactJian Zhang

Shanghai University of Sport

zhangjian@sus.edu.cn+86 135 2474 9688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026