Patients under general anesthesia
Conditions
Interventions
Conventional anesthesia group:Conventional intravenous anesthesia scheme
Less opioid anesthesia group:Use inhalation anesthesia to reduce the use of opioids.
Sponsors
The First Hospital of Nanchang
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age is 18~75 years old; 2. Plan to undergo non-cardiac surgery under general anesthesia; 3. ASA classification I~III.
Exclusion criteria
Exclusion criteria: 1.taking or relying on opioids; 2.Emergency surgery, extracranial surgery, transplant surgery and surgery under regional anesthesia; 3.The partial pressure of pulse oxygen is less than 95% when severe respiratory insufficiency or breathing air; 4.obstructive sleep apnea syndrome; 5.severe hepatic and renal insufficiency; 6.The patient is pregnant or nursing; 7.The patient is allergic to the drugs used in the study; 8.Outpatient surgery; 9.History of epilepsy or acute brain diseases; 10.Patients are unable to cooperate or refuse to participate in the study; 11.Have participated in other clinical studies in the last 3 months or need other operations in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine dosage within 24 hours after operation (converted into equivalent morphine dosage by MME conversion table); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hospitalization time;24 hours after operation, resting VAS score, used dose of analgesic pump, remedial analgesic dose, number of nausea and vomiting.;out PACU resting VAS score, used dose of analgesic pump;Postoperative hospitalization time;PACU resting VAS score, used dose of analgesic pump;Unplanned intubation;whether there are long-term complications and deaths;48 hours after operation, resting VAS score, used dose of analgesic pump, remedial analgesic dose, number of nausea and vomiting.;Unplanned admission to ICU;Whether or not to take analgesic drugs within three month after operation, and the type, dosage and duration of analgesic drugs.;PACU residence time, remedial analgesic dose during PACU;Whether or not to take analgesic drugs within one month after operation, and the type, dosage and duration of analgesic drugs.; | — |
Countries
China
Contacts
Public ContactXu Xinhua
The First Hospital of Nanchang
Outcome results
None listed