Hypoxemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 45 years old, American Society of Anesthesiologists physical status II to III; 2. BMI 30 to 55 kg/m^2; 3. Patients undergoing elective laparoscopic sleeve gastrectomy; 4. Patients voluntarily signed informed consent; 5. Meet the standard of PACU: (1) Complete reversal of neuromuscular blockade (TOF ratio >=0.9); (2) SpO2 > 95%; (3) End-tidal carbon dioxide was normal; (4) No edema of the upper respiratory tract; (5) Aldrete score >=9.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiovascular disease (ischemic heart disease, heart failure, severe angina attack, unstable angina within 6 months or myocardial infarction) and severe hypertension (systolic blood pressure (SBP) > 180 mmHg; or diastolic blood pressure (DBP) > 110 mmHg), hypotension (SBP < 90 mmHg); 2. Severe respiratory diseases (chronic obstructive pulmonary disease, respiratory failure, asthma, pulmonary bullae, recent upper respiratory tract infection, previous history of chest surgery) and hypoxemia (SpO2 < 92%); 3. Severe liver and kidney diseases; 4. Temporary change of surgical methods; patients whose operation duration was more than 3 hours; 5. Patients with known allergies to sufentanil citrate injection, propofol injection and other active ingredients or excipients used during surgery; 6. Patients with incomplete information or withdrawal requested by themselves or their family members.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia;Hypoxemia duration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of anesthesia-related adverse events after surgery;Patient comfort (VAS score);Arterial blood gas analysis (PaO2, PaCO2);Pulse oximetry; | — |
Countries
China
Contacts
The Fourth Affiliated Hospital of China Medical University