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Study on the Use of Tadalafil Fumarate for Postoperative Pain Relief and Sleep in Robot-Assisted Laparoscopic Radical Prostatectomy

Study on the Use of Tadalafil Fumarate for Postoperative Pain Relief and Sleep in Robot-Assisted Laparoscopic Radical Prostatectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120990
Enrollment
Unknown
Registered
2026-03-24
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain relief

Interventions

Control group:Provide sufentanil for postoperative analgesia
Experimental group:Provide postoperative analgesia with Tagilidine

Sponsors

Yantai Yuhuangding Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification I-III, age 30-65 years; 2. 19kg/m^2<BMI<24k g/m^2; 3. Patients undergoing robot-assisted laparoscopic radical prostatectomy; 4. After fully understanding the purpose and significance of this experiment, I voluntarily participate in this trial and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Allergic to the related medication; 2. Patients with a history of drug or alcohol abuse; 3. Patients with combined hearing and vision impairments or cognitive dysfunction; 4. Individuals with severe heart, lung, liver, or kidney dysfunction; 5. Postoperative ICU patient.

Design outcomes

Primary

MeasureTime frame
Area under the curve of the visual analog scale (VAS) for pain at rest and during activity within 24 hours postoperatively;

Secondary

MeasureTime frame
Ramsay sedation score at 24 hours post-surgery;Itching;Number of respiratory suppressions;number of rescue analgesic doses within 0-24 hours;Total number of PCA pump presses in 0-24 hours;total amount of rescue analgesics within 0-24 hours;Athens Insomnia Scale on 1 day before surgery, the day of surgery, and 1 day after surgery;time to first rescue analgesia after surgery;Number of vomiting episodes;Nausea and vomiting Apfel score;

Countries

China

Contacts

Public ContactCuicui Yu

Yantai Yuhuangding Hospital

yhdyyhhf@126.com+86 535 624 0341

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026