Postoperative Sore Throat after tracheal intubation in oral and maxillofacial surgery.
Conditions
Interventions
Lidocaine group:Lidocaine Glottic Surface Anesthesia
Lidocaine combined with dexamethasone Group:Lidocaine Combined with Dexamethasone for Glottic Surface Anesthesia
Saline Group:Saline spray applied to the glottis
Sponsors
The Affiliated Stomatological Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–45 years; 2. Scheduled for impacted tooth extraction, with an estimated procedure duration of 1–2 hours; 3. Requires nasopharyngeal video laryngoscope-guided tracheal intubation; 4. Preoperative fasting requirements completed; 5. Consents to participate in this study and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Refusal to participate in this study; 2. Emergency surgery; 3. Pre-existing throat conditions: acute laryngitis, chronic bronchitis, asthma, or upper respiratory tract diseases that may cause throat pain, including pre-existing symptoms such as sore throat, cough, or hoarseness; 4. Patients with a confirmed preoperative diagnosis of diabetes; 5. Patients undergoing general anesthesia within the past three months; 6. Patients with known allergies to lidocaine or dexamethasone; 7. Severe hepatic or renal impairment: ALT > 3 times the upper limit of normal, creatinine > 1.5 times the upper limit of normal; 8. Pregnant or lactating women; 9.History of difficult intubation, Cormack-Lane classification >= Grade III, or requiring multiple intubation attempts; 10. Critically ill patients (ASA classification >= Grade IV); 11. Currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of postoperative sore throat; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of severe postoperative hypotension within 12 hours after surgery;Incidence of Hypertension During Anesthesia and Endotracheal Intubation;Postoperative nausea and vomiting 12 hours after surgery;Incidence of Hypotension During Anesthesia and Endotracheal Intubation;Postoperative 24-Hour Recovery Quality Score;Time for postoperative throat pain to subside; | — |
Countries
China
Contacts
Public ContactSun Qiang
The Affiliated Stomatological Hospital of Nanjing Medical University
Outcome results
None listed