Neonatal sepsis
Conditions
Interventions
Clinically Confirmed Infection Group:None
Antibiotic Response Group:None
Initial Treatment Failure Group:None
Sponsors
Shanghai Changhai Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Admitted to the hospital with a diagnosis of "suspected neonatal sepsis." 2. Met the "suspected diagnosis" criteria according to the "Expert Consensus on the Diagnosis and Management of Neonatal Sepsis (2024 Edition)." 3. Completed screening for inflammatory markers (CRP or routine blood parameters) upon admission. 4. Gestational age > 32 weeks and birth weight >= 1500 grams.
Exclusion criteria
Exclusion criteria: 1. Severe congenital anomalies or genetic metabolic diseases. 2. Major perinatal injuries. 3. Extremely incomplete clinical data. 4. Withdrawal of treatment, transfer to another hospital, or death during hospitalization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Predictive efficacy of antibiotic decision nodes (AUC value);Differentiation of low-risk infection prediction models (C-index); | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory characteristics; | — |
Countries
China
Contacts
Public ContactLei Lei
Shanghai Changhai Hospital
Outcome results
None listed