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Cost-Effectiveness and Clinical Outcomes of Honey Dressings Versus Conventional Saline-Soaked Gauze in the Management of Open Wounds in a Tertiary Care Setting: A Randomized Controlled Trial

Cost-Effectiveness and Clinical Outcomes of Honey Dressings Versus Conventional Saline-Soaked Gauze in the Management of Open Wounds in a Tertiary Care Setting: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120944
Enrollment
Unknown
Registered
2026-03-23
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wounds

Interventions

Honey dressing group:Apply honey directly to the wound bed or immerse it in sterile gauze and fix it with a non-adhesive secondary dressing.
Normal saline dressing group:Dressing with normal saline

Sponsors

Sandeman Provincial Hospital, BUMHS Quetta
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients must be 12 years of age or older at the time of enrollment. 2. Presence of an open wound requiring management by secondary intention or preparation for delayed closure/skin grafting. 3. The wound must have a surface area of >=10cm^2 to ensure accurate measurement of healing time and cost-effectiveness. 4. Patient (or legally authorized representative) must provide written informed consent to participate in the study. 5. Patient is expected to remain hospitalized or available for follow-up at the hospital for the necessary period to assess the primary outcome (wound healing) and is compliant with the dressing protocol.

Exclusion criteria

Exclusion criteria: 1. Wounds due to thermal burns or chronic pressure ulcers of Grade III or IV severity. 2. Patients who are severely Immunocompromised (e.g., undergoing active chemotherapy, advanced HIV, or high-dose chronic immunosuppressive therapy). 3. Patients with uncompensated severe Malnutrition (e.g., serum albumin < 2.5g/dL or severe Anemia (Hemoglobin < 8 g/dL). 4. Wounds currently receiving or planned to receive Negative Pressure Wound Therapy (NPWT). 5. Wounds that are clean and closed primarily in the operating room. 6. Known allergy or hypersensitivity to honey or any dressing components. 7. Patients with a life expectancy of less than 6 months due to underlying non-surgical pathology.

Design outcomes

Primary

MeasureTime frame
Time to complete wound healing (days);Total treatment cost (PKR);

Secondary

MeasureTime frame
Time to clean wound bed (days);Bacterial clearance rate;Pain score during dressing change;

Countries

Pakistan

Contacts

Public ContactDr Sana Babar

Sandeman Provincial Hospital, BUMHS Quetta

dr.sanababar90@gmail.com+92 302 3840004

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026