postpartum depression
Conditions
Interventions
Esketamine group:After the fetus is delivered and the umbilical cord is cut, 0.25 mg.kg-1 esketamine is administered intravenously as a bolus (the total amount is prepared to 20ml)
control group:After the fetus is delivered and the umbilical cord is cut, 20ml of normal saline is administered by intravenous bolus injection.
Sponsors
Anyue County Hospital of Traditional Chinese Medicine (Ziyang Second Hospital of Traditional Chinese)
Eligibility
Sex/Gender
Female
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Those scheduled to undergo cesarean section under spinal anesthesia; 2. Those who clearly understand and voluntarily participate in this study, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. People with communication barriers; 2. Those with gestational hypertension or complicated with severe cardiovascular diseases; 3. History of hyperthyroidism; 4. Those with a history of drug abuse; 5. Those allergic to esketamine or with increased intracranial pressure, increased intraocular pressure, and increased intragastric pressure; 6. Those allergic to local anesthetics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EPDS score after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score at rest ;VAS motion score ;Usage of Patient-Controlled Analgesia Pump after Surgery ;Ramsay Sedation Score;BPRS+ score; | — |
Countries
China
Contacts
Public ContactLi Zhao
Anyue County Hospital of Traditional Chinese Medicine (Ziyang Second Hospital of Traditional Chinese)
Outcome results
None listed