Atelectasis
Conditions
Interventions
Group A:Titrate individualized PEEP based on static compliance for positive end-expiratory pressure ventilation
Group B:Positive end-expiratory pressure ventilation with a fixed PEEP of 8 cmH?O
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Adult patients (18-60 years old) scheduled for elective bariatric surgery, with ARISCAT score >=26 and ASA classification I~III.
Exclusion criteria
Exclusion criteria: 1.NYHA functional classification >=Class ?, with symptoms of cardiac insufficiency such as angina pectoris occurring within the past 6 months. 2.Complicated with asthma, moderate to severe chronic obstructive pulmonary disease (FEV1 < 80% of predicted value, FEV1/FVC < 0.7), pulmonary bullae, history of ARDS, persistent smoking within 1 week before surgery, or history of thoracic surgery. 3.Planned transfer to the intensive care unit (ICU) after surgery 4.Contraindications to the use of PEEP, such as increased intracranial pressure and pregnancy 5.Difficult airway known or suspected by the attending anesthesiologist, or significant craniomaxillofacial abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung Ultrasound Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| PaO2/FiO2;Peak inspiratory pressure;Plateau pressure;Driving pressure;Dynamic compliance;Static compliance;Heart rate;Mean Arterial Pressure;Pulse Oxygen Saturation; | — |
Countries
China
Contacts
Public ContactDong Su
The First Hospital of Jilin University
Outcome results
None listed