Severe acute pancreatitis
Conditions
Interventions
intervention group:Receive management based on the standardized enteral nutrition optimization protocol developed in this study
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with SAP after admission Diagnostic criteria for SAP: Persistent (>48 hours) organ dysfunction, accompanied by at least two of the following three criteria: (1) Persistent upper abdominal pain radiating to the shoulders and back; (2) Serum amylaseand/or lipase levels at least three times the upper limit of normal; (3) Abdominal imaging findings consistent with the radiographic changes typical of acute pancreatitis. 2. Age>=18 years, no severe cognitive impairment, and ability to cooperate with the nutritional therapy process 3. Informed consent 4. Enteral nutrition (EN) via nasogastric tube, nasojejunal tube, or jejunal stoma.
Exclusion criteria
Exclusion criteria: 1. Severe chronic gastrointestinal dysfunction present prior to admission (e.g., Crohn’s disease, short bowel syndrome). 2. Concurrent advanced malignant tumors or other terminal illnesses with a projected survival of less than 28 days. 3. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of feeding intolerance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional outcome; | — |
Countries
China
Contacts
Public ContactRong Wang
Renmin Hospital of Wuhan University
Outcome results
None listed