metabolic associated fatty liver disease
Conditions
Interventions
Moderate Metabolic-Associated Fatty Liver Disease Group:Standard therapy (diet and exercise)
Moderate Metabolic-Associated Fatty Liver Disease Group:Standard therapy (diet and exercise)+Spirulina
Severe Metabolic-Associated Fatty Liver Disease Group:Standard therapy (diet and exercise)
Severe Metabolic-Associated Fatty Liver Disease Group:Standard therapy (diet and exercise)+Spirulina
Sponsors
The Second Affiliated Hospital of Hainan Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 65 years; 2. Diagnosed with moderate to severe hepatic steatosis via liver ultrasound/magnetic resonance imaging, with no other liver diseases; 3. Patients consented to participate in the study and signed informed consent forms.
Exclusion criteria
Exclusion criteria: 1.History of liver cirrhosis or presence of and/or decompensated liver function, including ascites, hepatic encephalopathy, or variceal bleeding. 2.Other known causes of chronic liver disease. 3.History of or planned liver transplantation. 4.HIV-1 or HIV-2 infection. 5.Positive hepatitis B surface antigen. 6.Alcohol consumption >21 units/week for males or >14 units/week for females. 7.Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) levels >5 times the upper limit of normal. 8.Total bilirubin >1.3 mg/dL (>22.2 µmol/L). 9.Poor compliance. 10.Refusal to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver function; blood lipids;Degree of steatosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal Microbiota; | — |
Countries
China
Contacts
Public ContactFeihu Bai
The Second Affiliated Hospital of Hainan Medical University
Outcome results
None listed