None
Conditions
Interventions
Dexmedetomidine Group 1:Inject 1.5 µg/kg dexmedetomidine by nasal spray
Dexmedetomidine Group 2:Inject 2.0 µg/kg dexmedetomidine by nasal spray
Control group:Inject an equal volume of 0.9% normal saline in the same way
Sponsors
Jingmen People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who are suitable for undergoing painless gastroscopy under anesthesia; 2. Patients who have agreed to sign the informed consent form; 3. Age: 18 - 65 years old; 4. American Society of Anesthesiologists (ASA) classification: I-II grade.
Exclusion criteria
Exclusion criteria: 1. Unwilling to participate in this study; 2. With severe underlying diseases, which may affect postoperative recovery; 3. Patients with severe neurological and mental disorders, unable to cooperate with diagnosis and treatment; 4. Heart rate lower than 60 beats per minute; 5. Body mass index greater than 30 kg/m^2; 6. History of snoring, wheezing or obstructive sleep apnea syndrome, previous tracheotomy and difficult intubation, suspected gastric retention or gastric emptying disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ED50 of propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Induction time;The time of the first propofol injection; | — |
Countries
China
Contacts
Public ContactJunmin He
Jingmen People's Hospital
Outcome results
None listed