major depressive disorder(MDD)
Conditions
Interventions
MDD-3 (Verification Model for tACS Therapy Effectiveness):tACS Therapy
MDD-2 (Recovery Prediction Model for tACS Therapy):tACS Therapy
MDD-1 (tACS sham stimulation group):sham stimulation
Sponsors
ZhenJiang Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria for major depressive disorder as stipulated in the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders of the United States; 2.Age range 18-65 years old; 3.Has not received antidepressant medication treatment or has discontinued it for more than 6 weeks; 4.Han ethnicity; 5.Has received at least 5 years of formal education; 6.Right-handed; 7.Normal vision and hearing (or after correction); No language communication disorders.
Exclusion criteria
Exclusion criteria: 1.With a history of brain organic diseases and brain trauma, or with a history of endocrine diseases, or with abnormal blood tests, heart, liver, and kidney functions upon examination; 2.With a history of mental retardation, alcohol and drug dependence; 3.Pregnant and lactating women; 4.With contraindications for MRI scans such as electronic and metal implantations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prediction accuracy;Molecular genetic marker; | — |
Secondary
| Measure | Time frame |
|---|---|
| Emotional Symptom ;anhedonia ;Neurocognition;sensitivity;specificity; | — |
Countries
China
Contacts
Public ContactSun Jingjing
ZhenJiang Mental Health Center
Outcome results
None listed