None
Conditions
Interventions
Autism Spectrum Disorder Children Observation Group:None
The group of children with normal neurodevelopment:None
Sponsors
The Second Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Age: 2 - 14 years old, gender not limited, ASA I - III grade; 2. ASD children meet the diagnostic criteria for autism (DSM-5 or ICD-11); 3. NT children have no neurological or mental abnormalities; 4. Elective surgical procedures under intravenous anesthesia or general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Require special care or supervision from the court or social welfare institutions; 2. Have received intravenous anesthesia or general anesthesia within the previous 14 days or have pre-existing abnormal medication practices; 3. Have severe cardiovascular diseases, severe anemia, or liver and kidney dysfunction; 4. Have a difficult airway (modified Mallampati score III or IV); 5. Have obstructive sleep apnea-hypopnea syndrome (OSAHS); 6. Suspected to be allergic or contraindicated to propofol or other drugs specified in this trial; 7. Are judged by the investigator to be unsuitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characteristics of EEG changes following propofol induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Propofol induction, frequency of supplemental doses, and total intraoperative consumption;Intraoperative vital signs;Recovery time;Emergence delirium;Adverse events ; | — |
Countries
China
Contacts
Public ContactJi Muhuo
The Second Affiliated Hospital of Nanjing Medical University
Outcome results
None listed