Effect of Nasal Catheter Oxygen Inhalation on Dyspnea and Emergence Agitation in PACU Patients with Oral Endotracheal Intubation: A Randomized Controlled Study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600120871

Enrollment

Unknown

Registered

2026-03-20

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Respiratory Complications

Interventions

Intervention Group 1: Nasal Oxygen Only:In addition to routine PACU care, patients receive nasal catheter oxygen inhalation within 5–10 minutes after admission to the PACU. The oxygen flow rate is set

Intervention Group 2: Nasal Oxygen + Menthol:Based on the intervention of Group 1, at the time of nasal catheter connection, a nurse instills 2 drops of 0.5% menthol solution into each nostril using a

Comparator :Patients receive only routine PACU care, including standard mechanical ventilation support and monitoring according to clinical protocols. No additional nasal catheter oxygen therapy or me

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 65 years. 2.American Society of Anesthesiologists (ASA) physical status classification II–III. 3.Postoperative patients with oral endotracheal intubation admitted to the PACU and conscious (Richmond Agitation-Sedation Scale [RASS] score 0~2).

Exclusion criteria

Exclusion criteria: 1.Anatomical abnormalities or injuries that may interfere with nasal intervention (e.g., severe nasal deformity, trauma). 2.Concomitant severe cardiac disease (e.g., cardiac dysfunction with left ventricular ejection fraction [LVEF] < 50%). 3.Preoperative moderate-to-severe cognitive impairment (Mini-Mental State Examination [MMSE] simplified version score < 6). 4.Known allergy to menthol. 5.Patient refusal to participate in the study.

Design outcomes

Primary

Measure	Time frame
Dyspnea NRS Score;	—

Secondary

Measure	Time frame
MMSE Score(Mini-Mental State Examination simplified version);Richmond Agitation-Sedation Scale (RASS) score;Tidal Volume (VT);Respiratory Rate (RR);Airway Pressure (Paw);Arterial Partial Pressure of Oxygen (PaO2);Arterial Partial Pressure of Carbon Dioxide (PaCO2);Arterial Blood pH;	—

Countries

China

Contacts

Public ContactAbdusalam Asat

Xinjiang Medical University Cancer Hospital

1457019588@qq.com+86 157 3954 2612

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026