End-stage Diabetic Nephropathy, Diabetes with End-stage Renal Disease
Conditions
Interventions
Patients undergoing simultaneous pancreas-kidney transplantation:None
Sponsors
Second Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years. 2. Patients diagnosed with "end-stage diabetic nephropathy or diabetes complicated by end-stage renal disease". 3. Preoperative evaluation, surgery, perioperative management, and postoperative follow-up were conducted according to the clinical diagnosis and treatment protocols for simultaneous pancreas-kidney transplantation at our center. 4. Cardiac and myocardial cell structure and function were assessed using cardiac magnetic resonance imaging during the stable phase of post-transplantation renal and pancreatic function, as well as at the 6th and 12th months postoperatively.
Exclusion criteria
Exclusion criteria: Contraindications to CMR (surgically implanted devices such as cardiac pacemakers, cerebral aneurysm clips, cochlear implants, severe claustrophobia), as well as patients with severe cardiopulmonary dysfunction unable to tolerate CMR examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular ejection fraction, LVEF;Native T1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Amylase;Creatinine?; | — |
Countries
China
Contacts
Public ContactLi Guanghui
Second Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed