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Analgesic effect of bupivacaine liposomes compared with ropivacaine in thoracic paravertebral block

Comparison of analgesic effects of bupivacaine liposome and ropivacaine in parasternal block

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120861
Enrollment
Unknown
Registered
2026-03-20
Start date
2026-03-20
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

LB:10ml of bupivacaine liposome and 10ml of normal saline were injected into the intervertebral spaces T2-3 and T4-5 respectively, with a total injection volume of 40ml.
R:10ml of 0.25% ropivacaine and 5mg of dexamethasonenormal were injected into the intervertebral spaces T2-3 and T4-5 respectively, with a total injection volume of 40ml.

Sponsors

the First Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients scheduled for elective thoracoscopic partial pneumonectomy in this hospital; ASA class I-III, aged 18-75 years; no contraindications for TPVB; no contraindications for thoracoscopy; no chronic pain; good tolerance to anesthesia

Exclusion criteria

Exclusion criteria: Patients with severe cardiovascular, hepatic, or renal diseases; those with comorbid metabolic or endocrine disorders; individuals with puncture site infection or thoracic/spinal deformities; those undergoing antiplatelet therapy; patients with a body mass index (BMI) greater than 35 kg/m²; individuals with psychiatric disorders who cannot cooperate with the study; those allergic to local amide anesthetics or with a history of long-term benzodiazepine use; patients with a history of anesthetic drug allergies; and those who refuse to use analgesic pumps.

Design outcomes

Primary

MeasureTime frame
Quality of Recovery after Surgery Scale (QoR-15);

Countries

China

Contacts

Public ContactTeng Shiyong

Department of Anesthesiology First Hospital of Jilin University

tengsy@jlu.edu.cn+86 150 4410 7637

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026