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Safety of an Immediate Chlorhexidine Gluconate Gel Dressing Strategy following Peripherally Inserted Central Catheter placement in Breast Cancer Patients: A Randomized Controlled Trial

Study on Using CHG Dressings to Prolong the Time of First Dressing Change after PICC Placement in Outpatient Breast Cancer Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120836
Enrollment
Unknown
Registered
2026-03-20
Start date
2018-01-03
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

CHG group: In the CHG group, the PICC was secured with a CHG gel dressing (3M Tegaderm CHG I.V. Securement Dressing) post-insertion, with dressing changes scheduled every 5 to 7 days.
RD group:the RD group was managed with a 2 cm × 2 cm six-layer sterile gauze covered by the highly adhesive transparent dressing(3M Tegaderm HP transparent film dressing), with the first change at 24

Sponsors

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age over 18 years old; 2. Female; 3. Had a PICC catheter placed and regularly maintained at our hospital's intravenous therapy outpatient clinic.

Exclusion criteria

Exclusion criteria: 1. Pre-existing bloodstream infections or skin injuries at the puncture site; 2. Allergic to alcohol or CHG; 3. Known coagulation disorders, or on therapeutic anticoagulation, or risk of active puncture-site bleeding.

Design outcomes

Primary

MeasureTime frame
Bleeding;Medical adhesive-related skin injury;

Secondary

MeasureTime frame
Exit-site infection;Dislodgement;

Countries

China

Contacts

Public ContactSun Wenyan

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

s13910108189@126.com+86 10 6915 4098

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026