Malignant tumors of the liver, gallbladder, and pancreas
Conditions
Interventions
Gold Standard:Perform a biopsy or surgical procedure for pathological examination and obtain a definitive pathology report
Index test:Liquid Chromatography-Mass Spectrometry (Model: Waters Xevo G2-XS Q-TOF)
Sponsors
The First Affiliated Hospital of Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with newly diagnosed liver, gallbladder, or pancreatic masses can undergo puncture or surgery for pathological examination and obtain a definitive pathological diagnosis report; 2. Normal liver, kidney, and bone marrow function: WBC >= 3.5 × 10^9 /L, PLT >= 90 × 10^9 /L, and Hb >= 90 g/L; serum Cr <= 1.5 × ULN (upper limit of normal) and serum BIL <= 1.5 × ULN; ALT, AST <= 2.5 × ULN; 3. Age 18–70 years.
Exclusion criteria
Exclusion criteria: 1.Patients with hepatobiliary and pancreatic space-occupying lesions who are unable to obtain a definitive pathological diagnosis, or patients who cannot obtain a clear pathological diagnosis report. 2.Patients who have received chemotherapy, radiotherapy, immunotherapy, or targeted therapy within the past 3 months; 3.Patients with concomitant other malignancies; 4.Pregnant or lactating women; 5.Patients with coagulopathy (e.g., INR > 1.5) or a tendency to bleed; 6.Patients with severe infection or active autoimmune diseases; 7.Patients who are unable to cooperate with sample collection or follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive percent agreement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Negative agreement rate; | — |
Countries
China
Contacts
Public ContactShen Dongyan
The First Affiliated Hospital of Xiamen University
Outcome results
None listed