Endometriosis
Conditions
Interventions
Case group:None
Control group:None
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
Female
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: 1. Female individuals aged 18-49 years old; 2. Meeting the criteria for the control group or case group: Control group: No history of endocrine diseases. No history of hormone replacement therapy or no use of contraceptive pills and hormone-based drugs in the past 3 months. No metabolic, blood circulation, or systemic chronic diseases. No history of radiotherapy or chemotherapy. Not pregnant or in lactation. No excessive alcohol consumption in the past 3 months, or no long-term blood donation or blood transfusion. No reproductive organ deformities or ovarian surgeries, etc. Case group: Patients diagnosed with ovarian-type endometriosis by histological examination; 3. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Has a history of endocrine disorders. 2. Has a history of hormone replacement therapy or has taken contraceptive pills and hormone-based drugs in the past 3 months. 3. Has metabolic, circulatory, or systemic chronic diseases throughout the body. 4. Has a history of radiotherapy or chemotherapy. 5. Is pregnant or breastfeeding. 6. Has consumed large amounts of alcohol in the past 3 months, or has engaged in long-term blood donation or blood transfusion. 7. Has genital deformities or undergone ovarian surgery, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To elucidate the regulatory relationship between the cGAS-STING pathway and endometriosis fibrosis at the tissue and cellular levels.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Therapeutic targets for patients with endometriosis; | — |
Countries
China
Contacts
Public ContactLiu Yi
Wuhan Union Hospital, Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Outcome results
None listed