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Relationship between PLA2R Epitope Spreading and Prognosis in Patients with Membranous Nephropathy: A Multicenter Prospective Cohort Study

Relationship between PLA2R Epitope Spreading and Prognosis in Patients with Membranous Nephropathy: A Multicenter Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120798
Enrollment
Unknown
Registered
2026-03-19
Start date
2026-03-19
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary membranous nephropathy

Interventions

Health Observation Group:None
Lupus Observation Group:None

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The subjects voluntarily participated in the study and signed the informed consent form. 2. Patients diagnosed with membranous nephropathy and positive for serum PLA2R through renal biopsy. 3. Older than 18 years old. 4. Follow-up period longer than 12 months.

Exclusion criteria

Exclusion criteria: 1. Comorbid with other kidney diseases; 2. Comorbid with tumors, infectious diseases, rheumatic diseases, drugs and toxins, etc. as secondary factors; 3. Pregnant or lactating state; 4. Previous history of using hormones and immunosuppressants.

Design outcomes

Primary

MeasureTime frame
PLA2R epitope spreading status;—

Countries

China

Contacts

Public ContactQijun Wan

Shenzhen Second People's Hospital

liling156230@163.com+86 755 8336 6388

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026