Pulmonary hypertension due to left heart disease
Conditions
Interventions
Heart Failure with Preserved Ejection Fraction Combined with Pulmonary HypertensionHeart Failure with Reduced Ejection Fraction or Mildly Reduced Ejection Fraction Combined with Pulmonary Hypertension
Heart Failure with Reduced or Mildly Reduced Ejection Fraction and Pulmonary Hypertension:no
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 85 years. 2. Diagnosis of heart failure meeting the criteria outlined in the 2024 Chinese Guidelines for the Diagnosis and Treatment of Heart Failure: (1) Presence of heart failure symptoms and/or signs; (2) Elevated natriuretic peptide levels (BNP >=35 pg/mL or NT-proBNP >=125 pg/mL); (3) Evidence of cardiac structural and/or functional abnormalities. 3. Echocardiography indicates a pulmonary artery systolic pressure (or right ventricular systolic pressure) >=35 mmHg.
Exclusion criteria
Exclusion criteria: 1. PH due to other etiologies, such as pulmonary arterial hypertension, PH due to lung diseases and/or hypoxia, chronic thromboembolic PH, and PH with unclear and/or multifactorial mechanisms. 2. Conditions affecting complete blood count results, including hematological diseases, hyperthyroidism and hypothyroidism, presence of chronic inflammation or acute infection, etc. 3. Moderate or severe valvular stenosis or regurgitation. 4. Severe hepatic or renal dysfunction, malignant tumors, and other non-cardiac diseases limiting life expectancy. 5. Lack of complete blood count data or relevant clinical information. 6. Inability to cooperate with follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High and Low Systemic Inflammatory Response Index ;Pulmonary Artery Systolic Pressure; | — |
Countries
China
Contacts
Public ContactYan Liu
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed