Non-small cell lung cancer
Conditions
Interventions
Neoadjuvant chemo-immunotherapy group:NA
Neoadjuvant chemotherapy group:NA
Sponsors
Shandong First Medical University and Shandong Academy of Medical Sciences (Shandong Cancer Hospital &Institute)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years; 2. Patients pathologically confirmed with stage ?B-?A NSCLC; 3. Patients planned to receive neoadjuvant chemotherapy with or without immunotherapy; 4. Voluntary signed informed consent form; 5. Adequate hepatic and renal function; 6. ECOG performance status of 0 or 1; 7. Good renal function (serum creatinine (BUN) and serum urea nitrogen (Cr) <= 2.0 times ULN).
Exclusion criteria
Exclusion criteria: 1. Pregnancy; 2. Concurrent malignancies; 3. Contraindications to PET/CT; 4. Immunotherapy and chemotherapy contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major Pathological Response; | — |
Secondary
| Measure | Time frame |
|---|---|
| SUVmax;Tumor-to-Liver Ratio;Metabolic Tumor Volume;Total Lesion Uptake; | — |
Countries
China
Contacts
Public ContactSun Xiaorong
Shandong First Medical University and Shandong Academy of Medical Sciences (Shandong Cancer Hospital &Institute)
Outcome results
None listed