HBV-related acute-on-chronic liver failure
Conditions
Interventions
the group of CHB patients:None
the group of pre-acute-on-chronic liver failure patients:None
the group of acute-on-chronic liver failure patients:None
Sponsors
The Ninth Hospital of Nanchang
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with chronic hepatitis B (CHB), pre-acute-on-chronic liver failure (pre-ACLF) associated with hepatitis B, and hepatitis B-related acute-on-chronic liver failure (HBV-ACLF) hospitalized at the Ninth Hospital of Nanchang were enrolled in this study. The relevant diagnostic criteria were based on the Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2022 version) and the Guidelines for the diagnosis and treatment of acute-on-chronic liver failure (2025 version).
Exclusion criteria
Exclusion criteria: 1. Those with progressive deepening of jaundice caused by extrahepatic obstruction; 2. Other chronic liver diseases such as HCV and other hepatotropic viruses, non-hepatotropic virus infections, HIV infection, alcoholic liver disease, autoimmune liver disease, genetic metabolic liver disease and drug-induced liver injury; 3. Complicated with other malignant tumors (excluding those that have been cured); 4. Complicated with severe heart, lung, kidney, brain, blood, and neurological and mental system diseases; 5. Children, pregnant women and lactating women; 6. Subjects considered not suitable to participate in this study by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the lexel of Nucleocapsid-Antibody Complexes in peripheral blood serum; | — |
Countries
China
Contacts
Public ContactXizi Jiang
The Ninth Hospital of Nanchang
Outcome results
None listed