major depressive disorder
Conditions
Interventions
healthy control group:None
Sponsors
Hefei Fourth Peoples Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The depression group was included: 1. they met the diagnostic criteria for major depression in the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5); 2. aged 18-65 years; 3. Hamilton Depression Rating Scale-17 (HAMD-17) total score >=17 points; 4. vision or corrected-to-normal vision (>=1.0); 5. able to understand and sign the informed consent form. Healthy controls were included: 1. aged 18-65 years old; 2. no history of mental illness or family history of mental illness; 3. total HAMD-17 score =1.0); 5. able to understand and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Excluded from the depression group are: 1. the presence of other mental illnesses (such as schizophrenia, bipolar disorder, substance dependence, etc.); 2. the presence of serious physical diseases (such as epilepsy, stroke, history of craniocerebral trauma, etc.); 3. the presence of eye diseases that affect visual function (such as cataracts, glaucoma, retinopathy, etc.); 4. those who have participated in other clinical studies in the past month; 5. women who are pregnant or breastfeeding; 6. unable to complete test tasks or unwilling to cooperate with the research. Exclusions from the normal control group include: 1. those with severe physical diseases; 2. those with ophthalmic diseases that affect visual function; 3. those who have participated in other clinical studies within the past month; 4. women who are pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of auxiliary diagnosis of depression based on motion vision-EEG dual-modal fusion (AUC-ROC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Motion visual direction/speed discrimination threshold and psychophysical sensitivity index; | — |
Countries
China
Contacts
Public ContactHe Chen
Hefei Fourth Peoples Hospital
Outcome results
None listed