Helicobacter pylori infection
Conditions
Interventions
A group:Minocycline (100mg each time, twice a day)+Amoxicillin (1g each time, twice a day)+Kaplasen (20mg each time, twice a day) for 7 days
A group:Minocycline (100mg each time, twice a day)+Amoxicillin (1g each time, twice a day)+Kaplasen (20mg each time, twice a day) for 10 days
C group:Amoxicillin (1g each time, three times a day)+Kaplasen (20mg each time, once a day) for 14 days
Sponsors
Fuzhou University Affiliated Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients, aged between 18 and 80 years old. 2. Prior to treatment, no tetracycline, minocycline, doxycycline, or amoxicillin was used to eradicate Helicobacter pylori. No antibiotics, bismuth supplements, or traditional Chinese medicine were taken for 4 weeks prior to treatment, and no PPI, H2 receptor antagonists, or other medications were taken for 2 weeks. 3. Diagnosed as HP positive through C13 or C14 urea breath test and rapid urease test. 4. The patient is informed and agrees to participate in this study, and the medical records and follow-up records are complete.
Exclusion criteria
Exclusion criteria: 1.Individuals with severe primary diseases of the heart, lungs, kidneys, liver, and blood system, as well as those with weakened immunity. 2.Individuals with contraindications for amoxicillin, minocycline, and clopidogrel allergy. 3.Individuals with mental illnesses and communication barriers. 4.Pregnant and lactating women. 5.Combined with organic lesions such as gastrointestinal tumors and gastrointestinal bleeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate;Adverse reaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of clinical symptom remission; | — |
Countries
China
Contacts
Public ContactHuang Xueping
Fuzhou University Affiliated Provincial Hospital
Outcome results
None listed