Liver Neoplasms
Conditions
Interventions
Experimental group:Temporary Extrahepatic Bile Duct Occlusion: After completing the liver resection and hemostasis of the liver resection surface, rinse away any blood clots or eschar from the surface
if it shows signs of yellow staining, suture the corresponding bleeding site on the liver resection surface. Repeat the inspection until the gauze pad no longer shows yellow staining.
Control group:Traditional Gauze Test: After completing the liver resection and hemostasis of the liver resection surface, rinse away any blood clots or eschar from the surface with distilled water. Co
if it shows yellow staining, suture the corresponding bleeding site on the liver resection surface. Repeat the check until the gauze pad no longer shows yellow staining.
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who require elective liver resection for any reason (whether laparoscopic or open surgery) and meet the surgical criteria; 2. Patients aged >=18 and <=80 years; 3. Child-Pugh Class A liver function; 4. No severe comorbidities; 5. Complete clinical data; 6. Have received a comprehensive explanation of the study from the principal investigator, understand the study objectives, and have voluntarily provided a written informed consent form to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Age 80 years; 2. Patients undergoing emergency hepatectomy due to traumatic liver rupture; 3. Patients requiring biliary reconstruction and hepaticoenteric anastomosis; 4. Patients with preoperative biliary obstruction; 5. Patients with Child-Pugh Class B or C liver function; 6. Pregnant women, women who may become pregnant, or women who are currently breastfeeding; 7. Patients with immunosuppression; 8. Patients who have participated in other clinical trials or used unapproved or uninsured medicinal products within 3 months prior to enrollment; 9. Patients deemed unsuitable for participation in this study by the principal investigator or co-investigator due to clinical or ethical issues (e.g., unstable general condition or cognitive impairment affecting informed consent); 10. Patients with incomplete clinical data; 11. Patients unable to undergo follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of bile leakage following liver resection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Grading of Bile Leak Severity;Postoperative Changes in Liver Function;Length of hospital stay;Timing for removal of the drainage tube;Postoperative complications; | — |
Countries
China
Contacts
Public ContactLi Jiang
West China Hospital, Sichuan University
Outcome results
None listed