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Uric Acid Control Levels and the Risk of Diabetic High-Risk Foot in Patients with Type 2 Diabetes

The Dose-Response Relationship Between Uric Acid Control Levels and the Risk of Diabetic High-Risk Foot in Patients with Type 2 Diabetes: A Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120715
Enrollment
Unknown
Registered
2026-03-18
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic high-risk foot

Interventions

Case series:NA

Sponsors

The Third Affiliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. Diagnosed with type 2 diabetes according to the WHO 1999 diagnostic criteria during the baseline period; 3. Had at least two serum uric acid test records during the baseline period (at least 3 months apart); 4. No diagnosis of diabetic high-risk foot or diabetic foot disease (IWGDF Grade 0) at the start or throughout the baseline period.

Exclusion criteria

Exclusion criteria: 1. Presence of severe hepatic or renal insufficiency (eGFR < 30 ml/min/1.73m²), malignancy, or history of organ transplantation during the baseline period; 2. Long-term use of urate-lowering drugs during the baseline period; 3. Patients with above-ankle amputation.

Design outcomes

Primary

MeasureTime frame
newly onset diabetic high-risk foot;Time weighted average (TWA) uric acid;—

Countries

China

Contacts

Public ContactZhou Li

The Third Affiliated Hospital Sun Yat-sen University

1125323637@qq.com+86 188 1683 9865

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026