infectious disease
Conditions
Interventions
Observation Group:none
Sponsors
the First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The age of the subjects is >= 18 years old; 2. Clinically diagnosed as infectious diseases and stayed in ICU for more than 3 days; 3. Anti-infection treatment with vancomycin, meropenem, or voriconazole; 4. The first TDM of vancomycin, meropenem, or voriconazole, and the TDM was conducted during the ICU stay; 5. Undergo CRRT for 24 hours or no-undergo CRRT during the period from medication to TDM.
Exclusion criteria
Exclusion criteria: 1. Vancomycin and meropenem administration were not intravenous; 2. CRRT time is less than 24 hours during the period from medication to TDM blood collection; 3. Conversation between oral and injectable voriconazole during the medication to TDM blood collection period; 4. medication is administrated from different manufacturers During the period from medication to TDM blood collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Therapeutic drug monitoring specification rate;Therapeutic drug monitoring compliance rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Suitability of monitoring time for the first treatment drug;PK/PD compliance rate; | — |
Countries
China
Contacts
Public ContactSaiping Jiang
the First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed