Paroxysmal Atrial Fibrillation and Atrial Flutter
Conditions
Interventions
Simple loop pulmonary vein isolation group:Radiofrequency Ablation: Left atrial model constructed under 3D navigation guidance, circumferential pulmonary vein isolation (CPVI) performed using a pressu
Combined Ablation Group:Radiofrequency Ablation: Left atrial model constructed under 3D navigation guidance, circumferential pulmonary vein isolation (CPVI) performed using a pressure-sensing catheter
Sponsors
Nanjing Medical University First Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patient selection: Diagnosed with paroxysmal atrial fibrillation and accompanied by recorded atrial flutter (at least one episode of AF and AFL confirmed by 12-lead electrocardiogram, 24-hour ambulatory electrocardiogram or clinical records, which can coexist or be recorded separately by multiple electrocardiograms, and AFL can terminate spontaneously or convert to atrial fibrillation, with the duration of AFL episode < 12 hours). 2. Radiofrequency ablation therapy: Patients who have undergone circumferential pulmonary vein isolation or have undergone (or not) isthmus ablation of the tricuspid valve simultaneously. 3. Postoperative data: A 12-lead electrocardiogram is required after ablation
Exclusion criteria
Exclusion criteria: 1. History of previous cardiac ablation surgery; 2. Presence of severe structural heart disease (moderate or severe mitral regurgitation, hereditary hypertrophic cardiomyopathy, dilated cardiomyopathy, or other severe valvular diseases); 3. Thyroid dysfunction; 4. Contraindication to anticoagulation or inability/unwillingness to adhere to standard anticoagulation; 5. Patients unable or unwilling to commit to completing the scheduled follow-up as per the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Freedom from sustained supraventricular tachycardia lasting =30 seconds without antiarrhythmic drugs at 3 months post-single ablation procedure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative complications including stroke, pulmonary vein stenosis, cardiac perforation, esophageal injury, and death;Total operative time;Fluoroscopy time;Radiofrequency ablation time; | — |
Countries
China
Contacts
Public ContactChen Hongwu
Nanjing Medical University First Affiliated Hospital
Outcome results
None listed