Acute ischemic stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.age>=18 years; 2.Preoperative computed tomographic angiography (CTA) or magnetic resonance angiography (MRA) indicating large vessel occlusion (LVO) in the anterior circulation. 3.Endovascular treatment (EVT) performed within 24 hours of onset, or within 48 hours for patients with a significant ischemic penumbra identified by CT perfusion (CTP), supplemented with perioperative tirofiban as adjunctive therapy; 4.Stroke etiology classified as Large-Artery Atherosclerosis (LAA) according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) criteria.
Exclusion criteria
Exclusion criteria: 1.Pre-stroke modified Rankin Scale (mRS) score > 2; 2.History of intracranial hemorrhage or admission imaging showing evidence of intracranial bleeding; 3.Concurrent intracranial aneurysm or arteriovenous malformation; 4.Missing or incomplete key baseline data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intracranial hemorrhage; | — |
Secondary
| Measure | Time frame |
|---|---|
| 90-day mortality;Symptomatic intracranial hemorrhage;90-day mRS scores; | — |
Countries
China
Contacts
Army Medical Center of PLA