Research on the Development and Application of an Evidence-Based Oral Mucositis Intervention Protocol for Children with Acute Leukemia Undergoing Chemotherapy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600120663

Enrollment

Unknown

Registered

2026-03-18

Start date

2022-11-01

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute leukemia

Interventions

Control group:Implement routine care

Intervention group:Implement Routine Care + Oral Cryotherapy Intervention

Eligibility

Sex/Gender

All

Age

3 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Meet the clinical diagnostic criteria for acute lymphoblastic leukemia; 2. Age between 3 and 18 years; 3. Treated with the CCCG-ALL-2020 therapeutic regimen; 4. Currently undergoing induction remission therapy.

Exclusion criteria

Exclusion criteria: 1. Present with oral mucositis before chemotherapy; 2. Require radiotherapy; 3. Have cold-sensitive teeth; 4. Have comorbid mental illness or consciousness impairment; 5. Are currently participating in similar studies.

Design outcomes

Primary

Measure	Time frame
Incidence of oral mucositis;	—

Secondary

Measure	Time frame
Severity of oral mucositis;Duration of oral mucositis;Oral mucosa status during chemotherapy;	—

Countries

China

Contacts

Public ContactHuaying Yin

Children's Hospital Affiliated to Chongqing Medical University

940514550@qq.com+86 188 8336 9428

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026