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Development of a Machine Learning Model for Predicting the Efficacy of Immune Checkpoint Inhibitors in Chinese Cancer Patients

Predicting Immune Checkpoint Inhibitor Efficacy Using Routine Blood Tests and Clinical Data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120658
Enrollment
Unknown
Registered
2026-03-18
Start date
2025-05-01
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced malignant solid tumors

Interventions

The cohort of receiving immune checkpoint inhibitor:NA

Sponsors

The 960th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adult patients >=18 years old; 2. Patients with a clear histopathological diagnosis of tumor cases; 3. Receiving immune checkpoint inhibitor therapy alone or in combination with chemotherapy. 4. The ECOG-PS score is 0-2; 5. Receiving continuous anti-tumor therapy for >=2 cycles; 6. There is at least one measurable target lesion according to the modified criteria for the evaluation of solid tumor efficacy; 7. The patient's medical records and follow-up information are complete.

Exclusion criteria

Exclusion criteria: 1. Pathological diagnosis and disease stage do not meet the inclusion criteria. 2. Receiving immunotherapy for no more than 2 cycles; 3. Primary tumors; 4. Undergoing surgery or other invasive procedures in the past or during immunotherapy; 5. Participating in clinical trials. 6. The patient has autoimmune diseases or progressive cardiovascular and digestive diseases.

Design outcomes

Primary

MeasureTime frame
Overall survival;Progression free survival;Area Under the Receiver Operating Characteristic Curve (AUC-ROC);Accuracy;Sensitivity;Specificity;

Countries

China

Contacts

Public ContactJinmin Guo

The 960th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force

gjm90h@126.com+86 152 7519 1275

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026