extrinsic tooth stains
Conditions
Interventions
test group:Participants in the test group will use ShuKe SeXiu Whitening Toothpaste, brushing twice daily (morning and evening) under the supervision of study staff.
control group:Participants in the control group will use a control toothpaste free of whitening agents, brushing twice daily (morning and evening) under the supervision of study staff.
Sponsors
Peking University School and Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. In good general health, with 12 natural anterior teeth present, and without extensive restorations such as large fillings or crowns in the oral cavity; 2. Aged 18 to 65 years; 3. Presence of extrinsic tooth staining, with a mean Lobene stain score of =1.5; 4. Willing to sign the informed consent form and able to complete the clinical trial as required; 5. Not currently participating in any other similar clinical studies. Agrees not to use any non-study toothpaste, mouthwash, whitening strips, whitening pens, or similar products during the trial period; 6. Agrees to postpone any non-emergency oral examinations or treatments (including dental cleaning/scaling) until the end of the trial.
Exclusion criteria
Exclusion criteria: 1. History of allergy to any ingredient in the test toothpaste; 2. Received tooth whitening treatment within 1 month prior to the start of the study; 3. Presence of moderate or severe periodontitis; calculus at the gingival margin of the anterior teeth; or unresolved dentin hypersensitivity; 4. Presence of more than two open carious lesions or any oral mucosal lesions; 5. Women who are pregnant or breastfeeding, or planning to become pregnant during the study period; 6. Participation in any other clinical study involving oral/dental products during the study period; 7. Presence of intrinsic tooth discoloration, such as dental fluorosis or tetracycline-stained teeth; 8. Presence of any other serious oral disease or systemic disease (such as hematologic disorders, liver disease, diabetes, etc.); 9. Inability to brush teeth twice daily, in the morning and evening; 10. Any disease or condition that, in the opinion of the investigators, may affect the examination procedures or the subject’s safe completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lobene index; | — |
Countries
China
Contacts
Public ContactZhou Shuangying; An Na
Department of Periodontology, Peking University School and Hospital of Stomatology
Outcome results
None listed