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Construction of a head and neck malignant tumor organoid database and rapid intraoperative margin pathological assessment

Construction of a head and neck malignant tumor organoid database and rapid intraoperative margin pathological assessment

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120651
Enrollment
Unknown
Registered
2026-03-18
Start date
2025-08-11
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancers

Interventions

Gold Standard:Paraffin-embedded histopathological findings
Index test:Fluorescence probe N188-ICG

Sponsors

Guangdong Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with newly diagnosed or recurrent head and neck malignant tumors (including but not limited to squamous cell carcinoma and adenocarcinoma of the oral cavity, pharynx, and larynx, as well as nasopharyngeal carcinoma). 2. Patients with head and neck malignant tumors who have surgical indications and can tolerate surgery.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women. 2. Patients without a confirmed clinical diagnosis or who have undergone radiochemotherapy, immunotherapy, targeted therapy, or any other anti-tumor treatment within the past month.

Design outcomes

Primary

MeasureTime frame
Difference in fluorescence intensity;

Secondary

MeasureTime frame
Diagnostic performance of fluorescence signal (ROC curve);

Countries

China

Contacts

Public ContactQianhui Qiu

Guangdong Provincial People's Hospital

shui7515@126.com+86 135 4459 7585

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026