Stroke
Conditions
Interventions
The iTBS group:Intermittent Theta burst magnetic stimulation
The tDCS group:Transcranial direct current stimulation
Combined group:Intermittent Theta burst magnetic stimulation combined with transcranial direct current stimulation
Sponsors
Chuanbei Medical College Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the diagnostic criteria outlined in the "Diagnostic Key Points for Various Cerebrovascular Diseases" revised by the 4th National Cerebrovascular Disease Academic Conference of the Chinese Medical Association, confirmed by computed tomography (CT) or magnetic resonance imaging (MRI), and diagnosed by certified, experienced doctors as ischemic or hemorrhagic stroke; (2) Aged between 18 and 70 years, within 6 months of the first stroke; (3) Diagnosis of PSCI according to the "PSCI Management Expert Consensus (2017)" using the Mini-Mental State Examination (MMSE) scoring criteria: illiterate <=17 points, elementary education <=20 points; middle school education or above <=24 points; (4) No severe visual or hearing impairments, clear consciousness, and able to complete relevant assessments and tests; (5) Stable vital signs; (6) No skull defects, no intracranial metal, or other contraindications for iTBS/tDCS/fNIRS.
Exclusion criteria
Exclusion criteria: (1) Patients with cognitive impairment caused by neurological diseases other than head trauma or stroke; (2) Patients with aphasia, unstable arrhythmias, or other severe physical diseases; (3) Patients with skull defects, intracranial metal, or other contraindications for iTBS/tDCS/fNIRS; (4) Patients with a history of epilepsy; (5) Patients with visual or hearing impairments; (6) Patients with consciousness disorders; (7) Patients with fever, infection, organ failure, post-stroke depression, or similar conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA) score at the treatment endpoint; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination (MMSE) score at the treatment endpoint;Mandarin version Oxford Cognitive Screen (OCS) score at the treatment endpoint; | — |
Countries
China
Contacts
Public ContactJingyi Lin; Yinxu Wang
Chuanbei Medical College Affiliated Hospital
Outcome results
None listed